In 1970, the Archdiocese of Saint Paul and Minneapolis resolved to establish a mission in Latin America as a response to the directives of Pope John XXIII.

After Fr Don Schnitzius investigated various areas throughout Central and South America, it was decided that the Archdiocese of St. Paul and Minneapolis would help serve the Church in the area of Ciudad Guayana, Venezuela. The area of Ciudad Guayana resembled the Twin Cities in that it is made up of two very large cities – San Felix and Puerto Ordaz – that are separated by a large river, the Caroni River. This part of Venezuela had a population explosion with the establishment of various steel mills and was in great need of clergy.

The first missionaries from the Archdiocese of St Paul and Minneapolis worked at the parish of Virgin Del Valle (Virgin of the Valley Parish) in Puerto Ordaz. As the parish grew, the bishop in that diocese asked the priests of the Archdiocese to work at a second parish, the parish of Buen Pastor (Good Shepherd Parish) in San Felix. The priests of the archdiocese were aided in ministry by Franciscan Sisters from Little Falls, MN. The active parish of Virgin Del Valle was handed over to a Venezuelan pastor and the missionary team from the archdiocese was asked to start a new parish in San Feliz close to Buen Pastor Parish. Thus, the parish of San Francisco de Asis was established by priests from the Archdiocese of St. Paul and Minneapolis and the Franciscan Sisters of Little Falls.

The parish of Buen Pastor and San Francisco de Asis were subsequently transferred to a Venezuelan priest and priests of the archdiocese were then asked to take over the parish of Jesucristo Resucitado in San Felix. Since 1998, the Archdiocese of St. Paul and Minneapolis has been solely focused on pastoral and ministry to the many barrios of San Felix from the parish of Jesucristo Resucitado.